Publication on near real-time detection of spinal cord ischaemia
PAPAartis co-ordinator Prof Christian Etz and his collaborators have recently published the findings of a study investigating microdialysis of cerebrospinal fluid (CSF) as a potential method to detect spinal cord ischaemia (SCI) during aortic repair. The team showed it was possible to detect three markers of SCI in experimental models and in a small number of patients using the microdialysis method. Read more here:
This work supports a subproject of PAPAartis where we aim to identify clinically relevant markers of SCI in CSF and to develop an easily applicable bed-side test. Biomarkers for the real-time detection of emerging SCI would potentially provide time to intervene (e.g. to elevate systemic blood pressure and/or blood oxygen saturation) and would be of great benefit in preventing devastating complications such as paraplegia, particularly in the early postoperative period after TAAA repair.
Find out more about the PAPAartis sub-projects